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Use of Twins to Study Environmental Effects

By Christian, Joe C.

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Book Id: WPLBN0000240336
Format Type: PDF eBook
File Size: 0.2 MB
Reproduction Date: 2005

Title: Use of Twins to Study Environmental Effects  
Author: Christian, Joe C.
Language: English
Subject: Government publications, United Nations., United Nations. Office for Disarmament Affairs
Collections: Government Library Collection, Disarmament Documents
Publication Date:
Publisher: United Nations- Office for Disarmament Affairs (Unoda)


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Christian, J. C. (n.d.). Use of Twins to Study Environmental Effects. Retrieved from

Government Reference Publication

Introduction: Human experimentation is faced by everincreasing costs, more competition for available resources and the ever-present need to protect the experimental subjects from unnecessary risks. To counter these forces, extreme care must be taken to select the most powerful and efficient experimental designs for human epidemiological research. This paper explores the co-twin control model for use in epidemiological studies as an extremely efficient method of selecting controls which are matched genetically and environmentally as well as being the same age. Coupling paired comparisons of twins with sequential analysis is proposed as the most efficient method of studying low dose effects of environmental agents on human populations.


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