Molecular Biology and Biochemistry of Differentiation

By Harris, Stephen E.

Description
Government Reference Publication

Excerpt
Excerpt: At the heart of understanding the mechanisms involved in cellular differentiation in eukaryotic organism is an assessment of the genomic output, both qualitative and quantitative, during embryonic development and in the final differentiated organ systems. Since each somatic cell contains the same genome in terms of DNA content and sequence information, the mechanisms underlying cellular differentiation must be reflected in differential gene activation and repression of specific DNA sequences at various times during development. There must be control mechanisms capable of activating and selecting part of the total genetic potential while repressing other regions at different developmental stages or in different cell types. It is assumed that specific cellular products produced by one cell can and do influence the fate of gene expression patterns of other cell types in the surrounding environment of the differentiating system.

Book Id: WPLBN0000068570
Format Type: PDF eBook
File Size: 324,583 KB.
Reproduction Date: 2005

Title:

Molecular Biology and Biochemistry of Differentiation

Author:

Harris, Stephen E.

Volume:

Language:

English

Subject:

Government publications, United Nations., United Nations. Office for Disarmament Affairs

Collection:

Disarmament Documents

Subcollection:

Historic
Publication Date:

Publisher:

United Nations - Office for Disarmament Affairs (UNODA)

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